Andalusian experts indicate new elements responsible for instability in chromosomes

(University of Seville) The researchers state that RNA joins with DNA by chance or because of a disease, the structure of the chromatin, the protein envelope of the chromosomes is altered, causing breaks in the DNA. Gene mutations involved in the transcription and transport of RNA also cause damage in DNA, which they have shown is caused by changes in the chromatin. In these circumstances, the DNA cannot replicate itself naturally, generating replication stress, mutations and chromosome mutation...